Alum-precipitated Toxoid in Diphtheria Immunization

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Studies on Tetanus Toxoid: III. Antitoxic Response in Guinea Pigs Immunized with Tetanus Alum-precipitated Toxoid Followed by Tetanus Spores.

When an individual has been given one or more injections of tetanus toxoid and, at a later date, is injured and possibly infected with Clostridium tetani, what further precautions should be taken: (1) Administer antitoxin? (2) Give another injection of tetanus toxoid to accelerate the production of antitoxin? (3) Give no further treatment, depending on his present immunity to take care of the i...

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Diphtheria Immunization *

AT the beginning of the twentieth century diphtheria occupied a unique position in contrast to other infectious diseases. Its symptoms and course were well known and accurately described, the causal organism definitely recognized, and a specific remedy was available for its treatment, yet in spite of this wealth of scientific knowledge the control and prevention of the disease had proved a comp...

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COMMENTARY Humoral Antibody Formation in Infants Aged One to Three Months Injected With a Triple ( Diphtheria – Tetanus – Pertussis ) Alum - precipitated

OF ORIGINAL ARTICLE. The clinical syndrome known as Hirschsprung disease (HD), or congenital megacolon, had been recognized for more than a century. The pathogenesis of the dilation/hypertrophy of the colon without mechanical obstruction was puzzling, and the subject of great debate. Virtually all infants and children affected with this disorder died. The authors studied 26 patients with congen...

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Protection against group A streptococcus by immunization with J8-diphtheria toxoid: contribution of J8- and diphtheria toxoid-specific antibodies to protection.

A conformationally constrained, minimally conserved peptide from the M protein of group A streptococcus (GAS) has been defined. It consists of 12 amino acids from the C-repeat region within a non-M protein helix-forming sequence and is referred to as "J8." Here, we investigate the immunogenicity of a J8-diphtheria toxoid (DT) conjugate adjuvanted with the human-compatible adjuvants, SBAS2 and a...

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ژورنال

عنوان ژورنال: BMJ

سال: 1936

ISSN: 0959-8138,1468-5833

DOI: 10.1136/bmj.1.3917.208